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5-Amino-1MQ isn’t a peptide and it isn’t a stimulant. It’s a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), designed to optimise the cell’s internal “bookkeeping” rather than stimulate nerves or hormones.
By blocking NNMT, 5-Amino-1MQ preserves niacin (NAM) and methyl donors (SAM), freeing up key cellular resources for mitochondrial maintenance, energy production, and epigenetic regulation. In preclinical studies, this has led to smaller fat cells, increased energy expenditure, and reduced inflammatory signalling essentially letting your cells run more efficiently.
Researchers are exploring 5-Amino-1MQ for its system-wide metabolic and epigenetic effects, without directly activating receptors or hormonal pathways.
Precision and reliability are essential for research. CellPeptides provides:
• ≥99% purity 5-Amino-1MQ, pharmacological-grade, ready for in-vitro or preclinical studies
• Independent lab-tested certificates of analysis for transparency
• Fast, insured, temperature-controlled global shipping with tracking
• Flexible payment options, including crypto, credit card, or bank transfer
• Expert support for technical questions or study design consultation
Synthesised in our EU-based WHO/GMP and ISO 9001:2015 certified laboratory, our 5-Amino-1MQ gives you consistency and confidence in every batch.
5-Amino-1MQ selectively inhibits NNMT, the enzyme that methylates nicotinamide (NAM) to 1-methylnicotinamide (1-MNA). This has several cellular consequences:
• Preserves NAD⁺ — preventing NAM diversion boosts NAD⁺ levels, supporting mitochondrial enzymes like sirtuins.
• Protects methylation potential (SAM) — maintaining SAM:SAH balance supports epigenetic gene regulation.
• Reduces 1-MNA levels — a direct biochemical marker of NNMT inhibition.
• Promotes metabolic efficiency — adipocytes store less fat and show higher energy expenditure signals.
• Modulates inflammatory tone — improved redox and signalling reduces biochemical “noise.”
At the cellular level, this positions 5-Amino-1MQ as a metabolic and epigenetic “node,” impacting energy, fat storage, and cellular stress pathways without acting as a hormone or receptor agonist.
• NAD⁺ Optimisation – Supports mitochondrial function and sirtuin-guided repair
• Epigenetic Regulation – Maintains healthy methylation, supporting gene expression stability
• Fat-Cell Size Reduction – Adipocytes shrink and burn more energy in rodent models
• Metabolic Boost – Energy expenditure cues rise; systemic efficiency improves
• Inflammatory Modulation – Reduces pro-inflammatory signals via redox and signalling effects
• Biochemical Proof – Lowered 1-MNA levels demonstrate target engagement
Note: All effects are based on in-vitro and animal research. 5-Amino-1MQ is not for human use or dosing recommendations.
• Oral capsule studies: 50–100 mg/day, split into 25–50 mg BID; some protocols report 50–150 mg/day in 8–12 week cycles with breaks.
• Injectable formulations: 150–600 µg/day, often with step-up schedules over 4–12 weeks (note unit differences vs. oral capsules).
• Use our peptide/compound calculator to determine exact dosage for your model.
Reconstitute or prepare per study design, store according to lab safety protocols, and use within recommended stability periods.
• Metabolic researchers studying energy expenditure, fat storage, and mitochondrial function
• Epigenetic scientists investigating methylation balance and gene expression
• Preclinical labs exploring small-molecule modulators of NAD⁺ and sirtuin pathways
• Biohackers and academic groups modelling metabolic reprogramming and system-wide cellular efficiency
Every batch of 5-Amino-1MQ is made to exacting standards, letting you focus on research instead of reliability concerns:
• WHO/GMP & ISO 9001:2015 EU-certified synthesis
• ≥99% purity verified by independent lab reports
• Fast, insured global shipping with tracking
• Flexible payment including crypto
• Dedicated support for study design or ordering questions
Your research deserves reproducible results, and our 5-Amino-1MQ delivers consistency with every order.
DISCLAIMER
5-Amino-1MQ is for in-vitro and preclinical research only. It cannot be:
• Used in human clinical trials
• Administered to humans
• Supplied for human investigational use